Minoxidil not working? The answer may be in your genes
For roughly one in three people, minoxidil does not deliver the expected result. Often the reason is genetic. We explain why and how you can know in advance.
Minoxidil is one of the most common hair-loss treatments, and for many it works. But it is well established that for some people minoxidil delivers almost no result despite months of consistent use. If that has been your experience, the problem is probably not your discipline — the answer often lies in genetics.
Why minoxidil does not work for everyone
Minoxidil is not active in the form applied to the scalp. To stimulate follicles, the body must convert it into minoxidil sulfate. This conversion depends on the enzyme sulfotransferase, whose activity varies between people and is largely genetically determined. If enzyme activity is low, minoxidil's effect stays weak no matter how carefully it is used.
How a genetic test helps
TrichoTest analyses genetic markers related to follicle biology and drug response, helping estimate how well your profile supports minoxidil and other ingredients such as finasteride — before you start treatment. If minoxidil is unlikely to be effective, the report helps your doctor consider alternatives.
What to do if minoxidil has not helped
If you have used minoxidil for four to six months without visible results, do not simply increase the dose. It is wiser to find out which treatment actually matches your genetic profile. The report can be used together with your doctor or trichologist to build a new, personalised plan.
See how the test works or view the test price.
Frequently asked questions
Why does minoxidil not work for some people?
Minoxidil must be converted into an active form by the enzyme sulfotransferase. Its activity varies genetically, and when it is low, minoxidil stays weak.
Can a genetic test show whether minoxidil suits me?
TrichoTest assesses genetic markers related to drug response, helping your doctor predict how likely minoxidil and other ingredients are to suit you.
How long should I try minoxidil before drawing conclusions?
Results are usually assessed after four to six months. If there is no change, consider genetic testing.
What if the test shows minoxidil probably will not help?
The report then helps your doctor or trichologist choose alternatives better suited to your genetic profile.
Find out which treatment suits your genes
TrichoTest analyses 28 markers to help choose effective treatment. Price €390.